… in the brain’s waste clearance mechanisms. Disruptions in sleep, which are common in people with PD, have similarly … PD to investigate how enhancing a particular phase of the sleep cycle can promote natural brain clearance pathways, … that drugs that enhance the “slow wave” phase of the sleep cycle will boost the brain’s waste clearance …

… behavioral disorders, neuropsychiatric issues and sleep disorders, which severely impact quality of life. Our … symptoms, including anxiety, cognitive function and sleep dysfunction. To elucidate the compound's mechanism of … non-motor manifestations. … microglia … Neuroinflammation … Sleep Disorders … Parkinson’s Disease Therapeutics Pipeline …

… one can only be accomplished at the expense of the other. Sleeping in a head-up tilt position (HUTS) is an attractive … 1° tilt. Each HUTS treatment will be preceded by one week sleeping horizontally, so the total trial duration will be 9 …

… increasing the power of the studies. … Spain … Biomarkers … Sleep Disorders … Neuroimaging … Research Grant … Giulio …

… Study Rationale: REM sleep behavior disorder is well recognized as a prodromal … based on detailed characterization of REM sleep behavior disorder in a prodromal patient population. … in a seed amplification assay in individuals with REM sleep behavior disorder, along with co-pathology markers in …

… treatment and drug development. Our hypothesis is that REM Sleep Behavior Disorder (RBD) patients who years later … of previous studies at the Center for Advanced Research in Sleep Medicine of Hospital Sacré-Coeur Montréal. Spectral … options. March 2014 … Biomarkers … Spain … Neuroimaging … Sleep Disorders … Understanding Parkinson's Disease … Rapid …