… between neurodegeneration, mitochondria and the ubiquitin system. He has been studying Parkin since 2007 and has …

… entry for clinical, genetic and pedigree information. This system will also support a native “Global Statistical Test” … database or datamart. Project Description:  The informatics system (IS) incorporates all of the ‘clinical research …

… Cav1.3 calcium channels in heterologous expression systems, it is unclear whether they have the pharmacological … to determine whether when these molecules are administered systemically, they protect dopaminergic neurons against …

… addresses alterations of mitochondrial morphology in model systems of Parkinson’s disease including oxidative stress ( … insights into mechanisms of mitochondrial demise in model systems of oxidative stress-induced neuronal cell death …

… prior attempts to treat PD patients with GDNF used a pump system that infused the GDNF directly into the brain. … antibody, which crosses the BBB via endogenous transport systems. The antibody acts as a molecular Trojan horse, and …

… model and assess their long-term impact on the dopaminergic system. An optimal approach to these studies is to use … leading to the degeneration of the dopaminergic system. Such knowledge will be relevant to the understanding …