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Validation of a Blood-based Gene Expression Assay for Early Diagnosis and Monitoring Disease
… (production and regulatory) for providing the PDx test to health care providers. Further development includes testing …
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Stem Cells with Different Amounts of Alpha-synuclein as a Drug Discovery Tool
… stop Parkinson's disease progression. Objectives for Supplemental Investigation: We now aim to develop additional stem … in these cells. Lastly, we will evaluate the overall health of these cells and their ability to form networks, a …
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Further Validation of SIRT3 in a Parkinsonian Model
… levels will be elevated at two different stages of neuronal health: when neurons are healthy and when they are functionally impaired. The effect … nigra). If SIRT3 restores impaired neurons back to a healthy state, it is likely to be an effective therapy in …
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Discovery and Development of Novel Parkin Activators
… by eliminating damaged mitochondria and preserving neuronal health. Hypothesis: The first phase of the study will …
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Feasibility of Screening for Parkinson's Genetic Risk Factors in People of Asian Ancestry
… Bay Area Asian community, including community leaders, health systems and media outlets. Impact on …
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Studying GLP1 Receptor as a Therapeutic Target in Parkinson's Disease
… in brain cells and how this may ultimately affect the health of cells. Study Design: We have designed this study …