… a protein that spreads in the brain and nervous system. Current cerebrospinal fluid (CSF) tests require an …

… this toxic protein is by activating a natural cell-cleaning system called autophagy. Drugs that activate autophagy by …

… reach the brain through the vagus nerve and the circulatory system. A  2017 study  found an association between severing … in Parkinson’s, a lot of which was done through the Systemic Synuclein Sampling Study (S4). Three current …

… absorption and transport into the central nervous system, the models will be tested for proper functionality … starting from the periphery, entering the central nervous system and eventually causing degeneration of higher areas, …

… continuously for 24h/day, via a delivery pump system during two weeks, using different day and night … local reactions at the infusion site and no particular systemic adverse events, which matches the results obtained …

… Parkinson's Disease is Moving Towards a Biologic Staging System Recent biomarker advancements enable accurate … clinical symptoms. This proposal introduces a staging system, NSD-ISS, categorizing individuals by α-synuclein …