… and evolution of progressive changes in the dopamine system in Parkinson’s disease (PD) associated with LRRK2 … believe this will also be true for changes in other brain systems that may be involved even earlier than dopamine. … tomography (PET) to assess the function of other chemical systems in the brain, specifically serotonin and …

… Boston Scientific's Vercise deep brain stimulation (DBS) system for Parkinson's disease. This device has been … Abbott's Infinity DBS devices on the U.S. market. All DBS systems have the same basic components and work in similar … of neurology at Emory University in Atlanta about the new system, how it compares to the previously available ones and …

… Image by J.N. Eskra In 2015, recruitment began for the Systemic Synuclein Sampling Study (S4) . This important …

… diminished glutathione levels.  Cystine-glutamate exchange (system xc-) is a key regulator in the direct exchange of … glutathione.  Therefore, drugs designed to target system xc- should reduce oxidative stress and elicit … confirmed that our lead small molecules selectively target system xc- and effectively drive the exchange of …

… I talk with scientists on the potential role of the immune system and inflammation in Parkinson’s and how studying this … effect of Parkinson’s disease. Learn more about the immune system’s role in Parkinson’s disease by watching a webinar …

… promoting inflammation in the brain. As we age, the immune system becomes more "experienced," that is, effective in … able to respond to new infections. This aging of the immune system may play a role in PD. We have found evidence … protect against PD by limiting the ability of the immune system to become activated and cause brain inflammation. …