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In Vivo Distribution of α-Synuclein In Multiple Tissues and Biofluids in Parkinson’s Disease
September 1, 2020
… Objective: The Systemic Synuclein Sampling Study (S4) measured α-synuclein in multiple tissues and biofluids within the same patients with …
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Non-dopaminergic Systems in the Evolution of LRRK2 Parkinsonism
… and evolution of progressive changes in the dopamine system in Parkinson’s disease (PD) associated with LRRK2 … believe this will also be true for changes in other brain systems that may be involved even earlier than dopamine. … tomography (PET) to assess the function of other chemical systems in the brain, specifically serotonin and …
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New Deep Brain Stimulation (DBS) System Approved for Parkinson's
December 15, 2017
… Boston Scientific's Vercise deep brain stimulation (DBS) system for Parkinson's disease. This device has been … Abbott's Infinity DBS devices on the U.S. market. All DBS systems have the same basic components and work in similar … of neurology at Emory University in Atlanta about the new system, how it compares to the previously available ones and …
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Targeting System-xc for the Treatment of Parkinson's Disease
… diminished glutathione levels. Cystine-glutamate exchange (system xc-) is a key regulator in the direct exchange of … glutathione. Therefore, drugs designed to target system xc- should reduce oxidative stress and elicit … confirmed that our lead small molecules selectively target system xc- and effectively drive the exchange of …
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Findings from Systemic Synuclein Sampling Study (S4) Published
September 1, 2020
… Image by J.N. Eskra In 2015, recruitment began for the Systemic Synuclein Sampling Study (S4) . This important …
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Ask the PhD: Immune System’s Role in Parkinson’s Disease
October 16, 2019
… I talk with scientists on the potential role of the immune system and inflammation in Parkinson’s and how studying this … effect of Parkinson’s disease. Learn more about the immune system’s role in Parkinson’s disease by watching a webinar …