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Parkinson’s Disease Therapeutics Conference Showcases Progress Toward Better Treatments
… known to be highly heterogenous (different for everyone). Multiple speakers at the conference talked about better … invasive. In terms of treatments, the audience heard about multiple approaches. For example, mitochondria (the power … cells in the brain. However, another neurotransmitter system, the cholinergic system, has also been found to …
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SUPPLEMENT: Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Activity and Progression
… impact.” Octave has proven its precision- care platform in multiple sclerosis, including a multiplexed custom biomarker assay panel, now used in ~40 … of biomarker signatures to relevant endpoints and employ a systems biology approach to corroborate pathophysiology. …
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The Michael J. Fox Foundation Is Hiring
September 13, 2016
… organized, detail-oriented project manager to support multiple research initiatives focused on MJFF's clinical … organized, detail-oriented project manager to support multiple research initiatives focused on MJFF's sponsored … and a Cisco Administrator to maintain computer systems and networks aiming for the highest functionality. …
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Development of ALK4290 as a Novel Parkinson's Therapeutic
… Study Rationale: There is clear evidence that the immune system plays an important role in the development and … of pathologic inflammation, with potential effects on multiple symptoms associated with Parkinson's disease. …
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Pre-formed Fibril-seeded Synucleinopathy: Impact on Proinflammatory Cytokines and Contralateral Excitotoxicity
… aggregation and neurodegeneration of the nigrostriatal system following optimized intrastriatal unilateral … represent a pathophysiological mechanism that is common to multiple forms of sporadic PD. Lastly, we believe that …
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Effects of IL-10 on Neurodegeneration in Mutant Alpha-Synuclein Transgenic Models
… therapeutic approaches that target the immune system in PD. Project Description: In trying to … the anti-inflammatory cytokine IL-10 to the central nervous system of a transgenic pre-clinical model of … we would suggest that this study also open the door to multiple lines of therapeutically oriented research to …