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Up-and-Coming Parkinson’s Doctors Discuss Research and Care
April 20, 2020
… Judith diagnosed this patient with a rare presentation of multiple system atrophy (MSA), a disease related to Parkinson’s. The …
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Pharmacokinetics and CNS Distribution of IgG Antibodies: Quantitative Comparison of Blood-brain, Blood-CSF and CSF-brain Relationships After Intranasal and Intravascular Dosing
… (PD). However, achieving reliable, chronic central nervous system (the brain and spinal cord) delivery for molecules, … peripheral tissue levels will be measured and mapped using multiple techniques. In summary, we will comprehensively … will allow us to obtain critical, quantitative central and systemic distribution data for intranasally-applied …
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Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening
… bidirectional control of defined brain circuits in intact systems. Project Description: We will use technical … in a less advanced model; tunability (so it recapitulates multiple stages of the disease from mild to advanced in the …
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Alleviating late motor complications of Parkinson's disease by a continuous dopaminergic treatment with transdermal delivery of L-DOPA Pro-drug
… NeuroDerm Ltd. is developing a novel delivery system of levodopa for the treatment of Parkinson's disease. … solution for patients. NeuroDerm's new transdermal delivery system, which is designed to achieve a constant level of … toxicity study and an acute local irritation study in multiple preclinical models, NeuroDerm is planning to …
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MJFF Heads to Neuroscience 2018 Conference
November 1, 2018
… Neurodegenerative Disorders and Injury" and "Theme E: Motor Systems." Highlights, which include several MJFF-funded … 189: LRRK2 Mechanisms, Targets, and Pathways . Multiple sessions . Sunday, November 4, 2:45 pm … Disease: Therapeutic Strategies: Clinical Trials . Multiple posters . …
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