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Steve Xu, MD
… had direct experience developing physiological monitoring systems that incorporate multiple sensors requiring hardware and software …
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Vikram Khurana, MD, PhD
… tools to dissect protein-misfolding mechanisms in nervous system cell types. The team integrates genetic interaction … and matched stem cells. Dr. Khurana is a co-inventor on multiple patents, including for novel drug classes in …
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Nandakumar S. Narayanan, MD, PhD
… disorders. His research integrates clinical neurology, systems neuroscience, and neuromodulation, supported by multiple federal grants. With over 130 peer-reviewed …
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Valentina Fossati, PhD
… generated the first iPSC lines from people with Progressive Multiple Sclerosis and developed protocols to create key … and microglia — as well as brain organoids and co-culture systems. Dr. Fossati also sent the first patient-derived …
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Michelle L. Hastings, PhD
… in this process cause diseases such as spinal muscular atrophy (SMA), Peutz-Jeghers syndrome, Alzheimer's disease …
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Evaluation of a Specific DAT Inhibitor in Pre-clinical Models of Parkinson's Disease
… disease with deficits in motor, sleep, cognitive, and other systems, we propose to establish a “platform” of models to … in combination with levodopa may improve PD treatment in multiple ways. During the day, MLR-1017 administration would … MLR-1017 showed both behavioral and biochemical benefit in multiple experiments that modeled Parkinson’s-like symptoms. …