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G. Sridhar Prasad, PhD
… Inc., where he was lead crystallographer and core member of multiple drug discovery programs, including schizophrenia … in building and implementing fragment-based technologies in multiple organizations including Merck and Metabasis. He is …
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Laura Smith, PhD
… and the University of Nottingham (cognitive problems in multiple sclerosis), before returning to Kent for a … across projects on Parkinson’s disease, dementia, and multiple sclerosis. …
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Discovery of LRRK2 Target Engagement Ligands to be Used in Imaging Studies
… discovery of a neuroprotective agent for treatment of PD. Multiple mutations within the LRRK2 gene are associated with … is desirable. Project Description: We have identified multiple chemical series that inhibit LRRK2 kinase activity … imaging agent. The first year of the program will identify multiple lead compounds for radio-labeling. …
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Anna Quattropani, PhD
… optimizing drug-like small molecules with CNS exposure for multiple sclerosis and Alzheimer’s disease therapeutics. She … for progressive supranuclear palsy (O-GlcNAcase inhibitor), multiple sclerosis and an oxytocin receptor antagonist that …
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Sheng Luo, PhD
… Disease Research Center (ADRC). He is also PI of multiple projects regarding novel latent variable modeling … faculty statistician in numerous clinical trials and multiple Data and Safety Monitoring Boards. …
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Jian Peng, PhD
… framework for simultaneous dimensionality reduction of multiple heterogeneous biological networks. The latter … alpha-synuclein genetic network. Dr. Peng has received multiple awards in the field of computational biology, …