The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Inhibiting Programmed Cell Death to Reduce Axonal Degeneration and Brain Inflammation in Parkinson´s Disease
Study Rationale: The degeneration of neuronal axons is an early pathological feature of Parkinson’s disease (PD) and an attractive target for therapeutic intervention. We have demonstrated that a...
Research Grant, 2023Non-Invasive Method for Recovering Protein Biomarkers in Parkinson’s Disease
Study Rationale: There is a need for simple methods to improve the diagnosis of Parkinson’s disease (PD) before individuals ever experience symptoms. Focused ultrasound technology can alter the walls...
Biomarkers to Support Therapeutic Trials Program, 2023Using the Chemical Modification of Alpha-synuclein to Define Disease State and Facilitate Patient Stratification in Parkinson’s Disease
Study Rationale: Novel disease-modifying treatments for Parkinson’s disease (PD) are urgently needed as the prevalence of the disease is increasing and no cure is available. At this point, we have...
Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Targeting the Dopamine D1 Receptor for a Treatment of Parkinson’s Disease with Minimal L-DOPA-induced Dyskinesia
Study Rationale: L-DOPA is the primary drug used for treating the mobility loss that occurs in Parkinson’s disease (PD) due to decreases in dopamine. Although L-DOPA enhances mobility, chronic...
Research Grant, 2023Evaluation of a Digital Therapeutics (DTx) Mobile App and Algorithm for Personalized Medication and Treatment Plan Optimization for People with Parkinson’s Disease
Study Rationale: People with Parkinson’s disease (PD) have few options for keeping their symptoms under control. An app that could automatically monitor PD symptoms, like tremors, could allow users to...
Biomarkers to Support Therapeutic Trials Program, 2023Using Neurophysiology as a Stratification Tool for Synucleinopathy
Study Rationale: Although numerous disease-modifying drugs are being developed for Parkinson’s disease (PD), the current methods used to identify people suitable for clinical trials are costly...
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Our funding programs support basic, translational and clinical research from academia and industry.