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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Rapid Response Innovation Awards, 2007
    Development and Initial Characterization of an Enzyme-linked Immunosorbent Assay for the Candidate PD Risk Marker ST13

    Objective/Rationale:
    Clinical signs of Parkinson’s disease develop only after the death of around 70 percent of vulnerable dopaminergic neurons. Laboratory tests for PD are not currently available...

  • Rapid Response Innovation Awards, 2007
    Methylphenidate for the Treatment of Gait Impairment in Parkinson's Disease

    Objective/Rationale:
    The objective of this study is to explore the effects of methylphenidate on the gait of patients with Parkinson’s disease who are experiencing shuffling and freezing...

  • Rapid Response Innovation Awards, 2007
    Nanoparticle Gene Therapy for Parkinson's Disease

    In this research project we will determine the feasibility of condensing plasmid DNA into nanoparticles and using these nanoparticles to deliver their payload into cells of the central nervous system...

  • Rapid Response Innovation Awards, 2007
    A Novel Strategy for the Selection and Transplantation of Dopamine-Specified Human Embryonic Stem Cells

    In Parkinson’s disease (PD), neurodegeneration is largely confined to one discrete group of nerve cells that produce the chemical dopamine (DA). Since the death of most DA neurons almost always...

  • Community Fast Track, 2007
    Neoangiogenesis and Blood-Brain Barrier in L-DOPA-Induced Dyskinesia

    Levodopa is still the most effective treatment for Parkinson's disease, but has a great potential to induce abnormal involuntary movements (dyskinesia).

    Working on a pre-clinical model of PD, we have...

  • Rapid Response Innovation Awards, 2007
    Aberrant Striatal Morphology: Impact on Therapeutic Efficacy in PD

    While recent clinical trials of neural grafting for Parkinson’s disease (PD) are disappointing, rationale for "replacing" brain cells lost to disease remains strong. Many issues thought to underlie...

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