To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
DJ-1 Plasmids
DNA Plasmids
DNA Plasmids encoding various DJ-1 cDNA inserts
LRRK2 T1348N Mouse
Mouse Model
Mice expressing the T1348N mutant (GTPase-dead) form of LRRK2. RRID:IMSR_JAX:021829
Cell line stably lacking LRRK2 expression (KO) (Type: Raw 264.7 macrophages)
Immortalized Cell
RAW 264.7 macrophage cell line with a knockout of endogenous mouse LRRK2 protein using zinc-finger nuclease (ZFN)-assisted adeno viral vector (AAV) technology to generate a stable cell line.
EIF4G1 R1207H Mouse
Mouse Model
Mice expressing the R1207H mutant form of EIF4G1. RRID:IMSR_JAX:021827
VPS35 D620N Mouse
Mouse Model
Mice expressing the D620N mutant form of VPS35. RRID:IMSR_JAX:023409
DNAJ26 Plasmids
DNA Plasmids
DNA Plasmids encoding various DNAJ26 cDNA inserts
LEGEND MAX™ Human Alpha-Synuclein ELISA Kit*
Assay
ELISA kit developed in collaboration with Covance for measuring human alpha-synuclein protein in biological samples. The assay has been demonstrated to conform to AAPS performance criteria using CSF as a matrix. Please note, this assay was previously made available as an ECL ELISA but has since switched to Colorimetric.
LRRK1 KO Mouse
Mouse Model
Knockout of LRRK1 created by deletion of exons 24-29 of the LRRK1 gene in the C57BL/6N mouse strain. RRID:IMSR_JAX:016120
LRRK2 pT1491 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine1491 of LRRK2.
Alpha-Synuclein Antibody
Antibody
Rabbit monoclonal antibody directed against wild-type human alpha-synuclein. The antibody was mapped to amino acids 118-123 (VDPDNE).
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic