To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
-
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
-
Tools Consortium
MJFF is working with industry to develop priority tools.
-
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
RILPL1 Antibody
Antibody
Rabbit monoclonal antibody directed against total rodent/human RILPL1 protein. Suitable for immunoblot, immunoprecipitation, and immunocytochemistry experiments.
SNCA Multiplication iPSC Lines*
Human iPS Cell
Isogenic iPSC lines harboring a triplication , duplication, single copy, or KO of the SNCA gene derived from a patient with the triplication mutation. These lines were generated and kindly deposited by Birgitt Schuele at Stanford University into the MJFF Sponsored Tools Program.
Total DJ-1 Antibody
Antibody
Mouse monoclonal antibody directed against full length DJ-1. Ideal for use in immunoblotting or immunoassays.
iNDI-PD iPSCs
Human iPS Cell
iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) lines are available at JAX. These lines were developed in partnership with NIH, Chan Zuckerberg Initiative, and Aligning Science Across Parkinson's (ASAP) to include iPSC lines expressing PD-associated mutations in SCNA, LRRK2, GBA, PINK1 and PRKN as well as mutation-corrected isogenic revertant controls. An inventory of available lines can be found here: https://www.jax.org/jax-mice-and-services/ipsc/cells-collection
PPMI iPSCs
Human iPS Cell
Induced pluripotent stem cell (iPSC) lines are available through the PPMI repository. The repository includes lines from control, idiopathic PD, genetic PD (LRRK2, GBA, SNCA), genetic unaffected carriers (LRRK2, LRRK2/GBA, GBA, SNCA), and prodromal patients. Gene-revertant controls are available for select lines. An inventory of available lines can be found here: https://zenodo.org/records/10783308
Rab 10 Protein
Protein
Rab10 synthetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides. To be used as a control with the pT73 Rab1o protein. This protein was designed and generated by X'PROCHEM.
pT73 Rab 10 Protein
Protein
Phospho-T73 Rab10 synthetic phosphomimetic protein fragment (AA66-181) generated by native chemical ligation of recombinant peptides. This protein was designed and generated by X'PROCHEM.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic