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Jens Christian Schwamborn, PhD
… and Principal Investigator at the Luxembourg Centre for Systems Biomedicine, where he leads research on stem cells, …
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CDC Selects Parkinson's as One of the First Diseases Included in New Database
November 19, 2018
… , called the National Neurological Conditions Surveillance System (NNCSS). Parkinson’s is one of two diseases that … of the CDC’s working group to build and implement this new system. At a meeting earlier this year at the CDC’s …
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Estrogenic Neuroprotection and the Parkinson's Disease Phenotype
… slowing the degeneration of the nigrostriatal dopaminergic system in PD. This proposal will study several novel … estrogen analogs in a rat primary mesencephalic culture system and the most potent and efficacious compounds will be …
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Cutaneous Alpha-Synuclein Deposition — A Biomarker in Parkinson’s Disease
… alpha-synuclein deposition in the peripheral nervous system. Because PD has prominent manifestations in the autonomic system (which controls visceral functions like digestion, …
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The delta-specific opioid glycopeptide BBI-11008: CNS penetration and behavioral analysis in a preclinical model of levodopa-induced dyskinesia
December 18, 2020
… showed penetration of the blood-brain barrier (BBB) after systemic administration to rats, as well as profound central … it reduced the levodopa-induced locomotor AIMs by 50% after systemic injection. The N -methyl-D-aspartate receptor …
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Enhancing Access to Meaningful Data: Nebraska Parkinson’s Disease Registry
… (NPDR) will roll out a new electronic data collection system, enforce state statutes requiring that physicians … of Parkinson’s disease: Support of the NPDR electronic system implementation, operations and maintenance will …