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Overview of Alpha-Synuclein Models

As one of the hallmarks of Parkinson’s disease, alpha-synuclein (aSyn) pathology is a highly desired readout in model systems. There are many in vivo models available that use aSyn mutations, overexpression, or misfolding to trigger pathology, degeneration, and behavioral readouts. In this overview document you will find a list of commonly used aSyn-driven models of Parkinson’s disease. Please note, this list is by no means comprehensive--others are available that may suit your needs

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