… of a drug that inhibits synapse and neuronal loss, brain atrophy, cognitive impairment and the hallmark brain …

… the connections between neurons in the enteric nervous system, which regulates the gastrointestinal tract. This … anatomic and functional maps of macaque enteric nervous system (ENS) and central nervous system (CNS) PD-relevant … Parkinson’s Disease: Using powerful new technologies across multiple PD-relevant model systems, this project could …

… had direct experience developing physiological monitoring systems that incorporate multiple sensors requiring hardware and software …

… in this process cause diseases such as spinal muscular atrophy (SMA), Peutz-Jeghers syndrome, Alzheimer's disease …

… disease with deficits in motor, sleep, cognitive, and other systems, we propose to establish a “platform” of models to … in combination with levodopa may improve PD treatment in multiple ways. During the day, MLR-1017 administration would …  MLR-1017 showed both behavioral and biochemical benefit in multiple experiments that modeled Parkinson’s-like symptoms. …

… by the FDA for Phase I studies in humans, works through multiple mechanisms of benefit, including immune modulation … neuroprotection, in pre-clinical models of central nervous system (CNS) injury and disease. Translationally relevant … administration provides documented therapeutic benefit in multiple models of CNS disease and injury, including stroke, …