The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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T2T Validation - NOD2, 2025Assessing the Role Played by NOD2 in Murine Models of PD
Study Rationale: Brain inflammation has been associated with the development of Parkinson’s disease (PD). In search for factors that may influence inflammation that triggers PD, several groups have...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025SUPPLEMENT: A Novel Immunotherapy for the Treatment of Parkinson’s Disease
Study Rationale: There is currently no treatment that slows or stops the progression of Parkinson’s disease (PD). We are developing a novel therapeutic approach that targets neuroinflammation and...
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Research Grant, 2024SUPPLEMENT: Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Activity and Progression
Study Rationale: Managing and treating Parkinson’s is extremely challenging without the right tools and insights. According to the Michael J. Fox Foundation, “the need for objective Parkinson’s...
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De-risking Therapeutic Development for NOD2
Summary of Target and Rationale for Funding: NOD2 is a signaling protein that plays a central role in regulating immune and inflammatory pathways. Preliminary genetic data suggest a potential link...
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T2T Validation - NOD2, 2025Inflammatory and Regulatory Functions of NOD2 in the Setting of Parkinson’s Disease
Study Rationale: NOD2 is a signaling protein which has been found to be more abundant and more active in brain tissues of patients with Parkinson’s disease. Certain changes in the sequence encoding...
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Summer 2021 RFP: Expanding Biological Understanding of PD, 2025SUPPLEMENT: Urinary Biomarkers of Retromer Dysfunction in Parkinson’s Disease
Study Rationale: “Retromer” is a molecular machine that regulates the trafficking of many proteins within a cell. While a dysfunction of Retromer is now known to be central in triggering and driving...
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Our funding programs support basic, translational and clinical research from academia and industry.