The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Aligning Science Across Parkinson's, 2020Mapping the LRRK2 Signaling Pathway and Its Interplay with Other Parkinson’s Disease Components
Study Rationale:
Genetic mutations that lead to the activation of the enzyme LRRK2 are a major cause of inherited Parkinson's disease. We aim to combine the complementary expertise of our four... -
Aligning Science Across Parkinson's, 2020Role of PD-related Proteins as Drivers of Disease through Modulation of Innate and Adaptive Immunity
Study Rationale:
The hallmark motor impairments in Parkinson’s disease patients are due to the progressive loss of a special type of neuron in the brain using the chemical messenger dopamine. The... -
Aligning Science Across Parkinson's, 2020Tracing the Origin and Progression of Parkinson’s Disease through the Neuro-immune Interactome
Study Rationale:
While inflammation of the brain caused by immune cells has been implicated in Parkinson’s disease (PD), it is unknown whether these cells attacking the brain initiate the disease... -
Aligning Science Across Parkinson's, 2020Mechanisms Overwhelming Protein and Organelle Quality Control in Parkinson’s Disease
Study Rationale:
Abnormal protein aggregation and prion-like aggregate spreading are hallmarks of the degenerative cascades of sporadic and familial Parkinson’s disease (PD) and can damage cells... -
Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Identifying a Molecular Signature of DNA Damage in the Blood Cells of People with Parkinson’s Disease
Study Rationale: The instructions needed to govern the function of living things are stored in their cells’ DNA. In cell types that divide, such as blood or skin, DNA checked for damage and repaired...
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Fall 2021 RFP: Expanding Biological Understanding of PD, 2022Examining Fatty Acid Imbalances in Parkinson’s Disease
Study Rationale: In people with Parkinson’s disease (PD), alpha-synuclein proteins aggregate to form structures called Lewy Bodies (LBs). These LBs have recently been found to also contain lipid...
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Our funding programs support basic, translational and clinical research from academia and industry.