The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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MJFF Research Grant, 2011Implementation of PD GWAS meta-analysis results on the PDGene databaseObjective/Rationale: 
 The goal of this proposal is to analyze all available Parkinson’s disease (PD) genomewide association study (GWAS) datasets so that we can identify gene variants associated with...
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MJFF Research Grant, 2011Axonopathy induced by overexpression of human -synuclein in the rat nigrostriatal dopamine systemObjective/Rationale: 
 Observations made in brains from patients with Parkinson’s disease indicate that the disease may start at the level of the axons and that loss of the affected neurons occur later...
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Rapid Response Innovation Awards, 2011Blood-Brain Barrier Modification Using Heterotopic Nasal Mucosal Grafting for Enhanced Symptoms & Side Effects and Macromolecular Disease Modifying Drug Delivery in Parkinson's DiseaseObjective/Rationale: 
 One of the most significant problems in the treatment of Parkinson’s disease is the inability to provide continuous and high molecular weight drug delivery to the central nervous...
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LEAPS, 2011Supplement to 'Discovery of mGluR4 Potentiators for Symptoms & Side Effects and Disease-Modifying Treatment of PD'Promising Outcomes of Original Grant: 
 Activation or potentiation of metabotropic glutamate receptor 4 (mGluR4) is a promising new strategy for both Symptoms & Side Effects and disease-modifying...
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Rapid Response Innovation Awards, 2011A New Strategy to Ameliorate Chemically-induced Parkinson-like Symptoms by Engaging the Spinal Locomotor Circuitry with Epidural StimulationObjective/Rationale: 
 Our objective is to determine if we can change the level of excitability of the spinal cord circuitry that controls posture and locomotion so that the sensory information derived...
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MJFF Research Grant, 2011Generation of Alpha-synuclein Filament Protein and Characterization of Alpha-synuclein Rabbit Monoclonal AntibodiesObjective/Rationale: 
 Aggregation of alpha-synuclein plays a pivotal role in the development of Parkinson’s disease. This subproject focuses on supporting the MJFF initiative of generating monoclonal...
 
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Our funding programs support basic, translational and clinical research from academia and industry.