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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • MJFF Research Grant, 2008
    Evaluation of Gastrointestinal Motility in Parkinsonian Rodents

    Objective/Rationale:
    Gastrointestinal (GI) symptoms, such as nausea, bloating, and constipation occur in nearly every patient afflicted with Parkinson’s Disease (PD) at some point in their illness...

  • MJFF Research Grant, 2008
    Are Anti-Parkinsonian Treatments Disease Modifying?

    Objective/Rationale:
    Current treatments of Parkinson’s disease are not thought to slow the progression of the disease but just appear to result in temporary relief of symptoms. There is some evidence...

  • MJFF Research Grant, 2008
    QE3 Trial Ancillary Biomarkers Study

    Objective/Rationale:
    The QE3 trial is a large multicenter clinical trial designed to determine whether the nutritional supplement coenzyme Q10, which traps a potentially dangerous type of chemical in...

  • Target Validation, 2006
    Identification of therapeutics that protect against toxins and genes implicated in Parkinson’s disease via the Forkhead-mediated transcription pathway

    Loss of dopaminergic neurons is one of the cardinal features of Parkinson’s disease. Medications that can delay or prevent dopaminergic loss could be beneficial in treating PD, but the optimal...

  • Target Validation, 2007
    Targeting Urate: A Molecular Correlate of Both Risk and Progression in PD

    Objective/Rationale:
    Urate (a natural antioxidant, caffeine analog and DNA metabolite) is the first molecule linked to both the risk of typical Parkinson’s disease and its rate of progression. Higher...

  • Rapid Response Innovation Awards, 2007
    Potential Utility of Novel CNS-active Experimental Therapeutics for Parkinson's Disease

    Objective/Rationale:
    Evidence suggests that overproduction of inflammatory molecules, called proinflammatory cytokines, from glial cells in the brain can contribute to nerve cell death and accelerate...

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Our funding programs support basic, translational and clinical research from academia and industry.

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