The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Cognition Biomarkers, 2013Insulin-like Growth Factor-1 and DAT Imaging as Biomarkers of Early Cognitive Impairment in Parkinson’s Disease
Objective/Rationale:
Evidence supports that the protein insulin-like growth factor-1 (IGF-1) may be involved in cognitive deficits. An earlier study found that low serum IGF-1 levels... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Validating the Montreal Cognitive Assessment for the Diagnosis of Mild Cognitive Impairment in Parkinson's Disease
Objective/Rationale:
Dementia affects up to 80 percent of Parkinson’s disease patients, and the prevalence of other dementias including Alzheimer’s disease is high in this age group. A need exists for... -
Defining Cognitive Phenotypes of Parkinson's Disease, 2011Cognitive Phenotypes in Parkinson's Disease: Anatomical and Functional Correlates
Objective/Rationale:
Cognitive impairment with and without dementia is frequent in Parkinson's disease (PD). However, there is a high heterogeneity in the clinical presentation of these cognitive... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011Development of Multimodal Imaging Biomarkers for Cognitive Dysfunction in Parkinson's Disease
Objective/Rationale:
By the time a person with Parkinson’s disease (PD) meets diagnostic criteria for dementia, the brain has already been ravaged. Unfortunately, current clinical, neuropsychological... -
Cognitive Deficits and Mood Disorders in Parkinson's Disease, 2008Neuroimaging Markers Predict Cognitive Decline in PD
Objective/Rationale:
Isolated cognitive impairments are common in PD; they increase in number and severity with advancing age and motor disability but their relation to the risk of developing dementia... -
Defining Cognitive Phenotypes of Parkinson’s Disease, 2011Bioanatomical Phenotype of Parkinson's Disease With and Without Cognitive Impairment
Objective/Rationale:
Mild cognitive impairment (MCI) and dementia are common in Parkinson’s disease. However, presently, it is difficult to recognize which aspects of cognitive changes are...
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