The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Access to Data and Biospecimens, 2015BioFIND: Analysis of A-beta, Tau and P-tau in CSF Samples
Study Rationale: Mixed pathology is common in all neurodegenerative diseases including Parkinson’s disease (PD). Three cerebrospinal fluid (CSF) biomarkers, Ab1-42, t-tau and p-tau181, provide an...
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PD Subtypes, 2007Defining PD Subtypes Based on Patterns of Long-term Outcome
The purpose of our study is to identify Parkinson’s disease subtypes based on how individuals are doing approximately seven to eight years after diagnosis. Some patients have few symptoms at this time...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2025GBA1 Consortium: Joint Analysis to Inform Clinical Trials
Study Rationale: Variants in the GB1A gene represent the most important genetic risk factor for Parkinson’s disease (PD) across the globe. However, different GBA1 variants are associated with varied...
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PPMI Data Challenge, 2016Subtyping Parkinson’s Disease with Deep Learning Models (2016 PPMI Data Challenge Winner)
Study Rationale:
As Parkinson's disease (PD) is highly heterogeneous, identifying coherent PD subtypes is crucial for understanding the underlying mechanism of the disease and designing and testing... -
Target Advancement Program, 2016Alpha-synuclein Toxicity in LRRK2 Pre-clinical Models and Rescue by LRRK2 Silencing
Study Rationale:
Genetic mutations that alter the function of the LRRK2 protein increase the risk of developing a form of Parkinson's disease (PD). Age and other environmental factors combine with... -
Rapid Response Innovation Awards, 2012A Genetic Strategy to Restore Impaired Noradrenergic Function by Increasing Expression of Noradrenergic Phenotypes in the Locus Coeruleus in Parkinson’s Disease Pre-clinical Models
Objective/Rationale:
Compelling evidence demonstrated that a dysfunction of the locus coeruleus (LC)-
noradrenaline (NE) system in the brain not only contributes to alterations in
cognitive and motor...
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Our funding programs support basic, translational and clinical research from academia and industry.