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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Research Grant, 2019
    PET Tracer to Support Trials of Drugs Inhibiting Neuroinflammation via the NLRP3 Inflammasome

    Study Rationale:
    Chronic inflammation of immune cells our brains is now believed to be associated with the onset and progression of Parkinson’s disease. These cells produce a target in Parkinson’s...

  • Research Grant, 2018
    The Effect of Psychological Stress on the Symptoms of Parkinson's Disease

    Study Rationale:
    Many people with Parkinson's disease (PD) experience chronic stress and associated disorders, such as depression, anxiety or both. Furthermore, many people with PD notice worsening of...

  • Alpha-Synuclein Biology and Therapies, 2019
    Studying the Impact of Alpha-synuclein on Fatty Substances to Identify New Parkinson's Disease Drug Targets

    Study Rationale:
    Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). It can attach itself and interact with fatty substances called lipids and fatty...

  • Research Grant, 2018
    Studying Measures of LRRK2 Activation and Lysosomal Dysfunction in Parkinson's Disease

    Study Rationale:
    As new, targeted therapies for Parkinson's disease (PD) enter clinical trials, biomarkers -- objective measures of disease --become increasingly important as tools for matching people...

  • Research Grant, 2019
    Diagnosing Early-Stage Parkinson’s Disease via a Urine Test for Extracellular Vesicles

    Objective/Rationale:
    There is a great need to develop new, readily accessible biomarkers — objective measures of disease — from biofluids (blood, urine, saliva or cerebrospinal fluid) for early...

  • Research Grant, 2018
    Developing New Drugs that Deactivate Deubiquitinase Proteins for the Treatment of Parkinson's Disease

    Promising Outcomes of Original Grant:
    In our past studies, we aimed to identify small molecule inhibitors of proteins called deubiquitinases (DUBs), i.e., chemicals that makes DUBs unable to perform...

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Our funding programs support basic, translational and clinical research from academia and industry.

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