The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Extracellular Vesicles from Urine as Non-invasive Biomarkers
Study Rationale:
Parkinson's therapeutic development has suffered because Parkinson's symptoms develop only after significant brain degeneration has occurred, leaving significant time between disease... -
Research Grant, 2018Examining GCase Activity in People with REM Sleep Behavior Disorder
Study Rationale:
Approximately 80 percent of people with REM sleep behavior disorder (RBD) will develop a neurological disorder such as Parkinson's disease (PD). GBA mutations are the most frequent... -
Research Grant, 2019Discovery and Development of Parkin Activators as Therapies for Parkinson’s Disease
Study Rationale:
Impaired mitochondria are a shared feature of Parkinson's disease (PD). Thus restoration of mitochondrial function offers a therapeutic avenue to slow the progression of PD. Parkin... -
Research Grant, 2018Development of Experimental Setups Using New Antibodies to Detect Alpha-synuclein in Cerebrospinal Fluid
Study Rationale:
Research studies have yet to clearly explain whether alpha-synuclein oligomers -- clumps of protein alpha-synuclein -- in biologicals fluids can be used in clinics as measures of... -
Research Grant, 2018Evaluation and Comparison of Existing Tests for Alpha-synuclein
Study Rationale:
An increase in the levels of alpha-synuclein -- a sticky protein that clumps in the brains of people with Parkinson's disease (PD) -- has been directly linked to an increased risk of... -
Research Grant, 2018Assessing the Effects of the Glucosylceramide Lipid on Protein Clumping
Study Rationale:
Changes (mutations) in the GBA1 gene cause Gaucher disease, a rare condition that causes fatty substances to build up and organs to swell, and increase the risk of Parkinson's disease...
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Our funding programs support basic, translational and clinical research from academia and industry.