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Xenon inhalation to reduce L-Dopa-induced dyskinesia
… however long-term use leads to disabling levodopa-induced dyskinesia (LID) in the vast majority of patients. NMDA … will be studied in a pre-clinical model of levodopa-induced dyskinesia. A xenon/oxygen mixture will be administered to …
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The Unified Dyskinesia Rating Scale (UDysRS): Clinimetric Testing Program
… issues for prevention and management is drug-induced dyskinesia. Dyskinesias are abnormal and involuntary movements that …
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Enhanced Dopamine Availability, Prolonged Activity and Improved Dyskinesia Profile After Administration of Selectively Deuterated Levodopa
… loss of anti-parkinsonian effect and a lower degree of dyskinesias. Anticipated Outcome: The synthesis of a major …
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Lentivirally-Delivered GRK2 and GRK6 for Decreasing Severity of Levodopa-induced Dyskinesia
… recently shown that, in the context of levodopa-induced dyskinesias, the debilitating motoric manifestation that …
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Dipraglurant for Levodopa-Induced Dyskinesia Pre-phase IIB Studies
… Efficacy of ADX48621 in the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease Study Rationale: … in particular, has shown significant effects in reducing dyskinesia in a pre-clinical model of Parkinson’s disease …
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Multi-single Unit Electrophysiological Characterization of Dyskinesia Induced by Dopamimetic Drugs
… phenomena, it is known that these complications, named 'dyskinesia', are accompanied by a dramatic reduction in the … disease. More recently, it has been proposed that the dyskinesia might also be accompanied by an increased …