… chronic administration induces abnormal movements termed dyskinesias. Dyskinesias are caused by imbalances in …

… The primary objective of this proposal is to determine if a prodrug of acamprosate could inhibit … shown to inhibit glutamate release and is used clinically for the treatment of alcohol relapse.  XenoPort-sponsored … of Parkinson’s disease.  Unfortunately, this therapy is complicated by inducing potentially disabling involuntary …

… Objective/Rationale: The mu opioid receptor (MOR) has long been proposed as an appealing target for managing levodopa-induced dyskinesia and therefore … test antagonists of the kappa and delta receptors to get a comprehensive analysis. The project therefore aims to …

… Many people with Parkinson’s disease eventually develop dyskinesias [dis-kuh-NEE-zhuhs] — abnormal and unwanted …

… of serotonin neurons in the induction and maintenance of dyskinesias in grafted and L-DOPA-primed animals Levodopa, …

… disease and use of Parkinson's medications are called dyskinesia. In our latest podcast Christopher Bishop, PhD, of Binghamton University, discusses what may cause dyskinesia with medication use. "There are two sides to …