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Microbiome Biomarkers for Early-stage Detection and Stratification of Parkinson's Disease
… Study Rationale: Parkinson's disease (PD) research benefits from knowledge of disease-specific risk … microbiome-derived small molecule signatures may provide an early means of diagnosing PD. Study Design: Our … the identified signatures will need to be translated into a clinically applicable test. …
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Parkinson's Disease Research Database
… disease. Characterization of these models provides insight into disease pathogenesis and critically informs … to track, creating a barrier to effective and efficient research. Hypothesis: This project aims to accelerate PD … loss, dopamine deficiency and motor impairment. Impact on diagnosis/treatment of Parkinson's disease: This resource …
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How I Told My Kids About My Parkinson's Diagnosis
March 28, 2012
… we’re going to start giving our allowances to Parkinson’s research because we want you to be better.” Somehow I held … them about some of the more common technical terms. Take into consideration their age and maturity level when … information and face everyday life. We recognized very early on that in most cases the reaction of our daughters …
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Role of Phosphodiesterase 10A in Early Sporadic Parkinson’s Disease
… expression in brain areas related to movement is a very early phenomenon in the clinical course of PD. Study Design: We will assess PDE-10A in people with early, untreated PD using a brain scan called positron … in PD such as the loss of dopamine transporter. Impact on Diagnosis/Treatment of Parkinson’s Disease: We …
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Neuromelanin in Circulating Phagocytes May Reveal Early Neurodegeneration in Parkinson's Disease Supplement
… This grant builds upon the research from a prior grant: Neuromelanin in Circulating Phagocytes May Reveal Early Neurodegeneration in Parkinson’s Disease Promising … the development of Parkinson’s disease, but by the time the diagnosis is made it may already be too late as many nerve …
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New Collaboration Seeks to Incorporate Patient Feedback into Clinical Trials
October 20, 2016
… announced a new initiative to incorporate patient feedback into the design of clinical trials, in partnership with The … to integrate patient preferences on benefits and risks into trials. MDIC hopes the pilot's learnings will be … “People with a disease like Parkinson's can be more than research subjects; we can be partners in the design and …