… Symptoms Many of the motor symptoms of Parkinson’s result from a decrease in dopamine, a brain chemical that helps … PD vaccine clinical trial. The study draws on evidence from pre-clinical studies that suggest their vaccine helps clear clumps of alpha-synuclein from the brain, potentially slowing disease progression. If …

… compared to levels in healthy controls. These findings were from a subsample of the 600 PPMI participants, so our next … in clinical study; we’ve funded a trial testing a vaccine from AFFiRiS AG that targets and helps remove the … company Biogen Idec. Loss of GCase enzyme activity, from mutations in the GBA1 gene, has been linked to …

… PPMI by opening its doors to data and biospecimen requests from scientists around the globe. The first study using PPMI … 126,000 data downloads and 30 requests for biospecimens from the landmark biomarkers study. “The more people looking … PhD, vice president of research programs 6. We’re learning from what didn’t go as planned. Ceregene, Inc. announced …

… Yes No Would you like to receive email communications from The Michael J. Fox Foundation? Yes No There will be … this event. If people attending in your party would benefit from live translation, please let us know how many headsets … the checkbox, I agree to receive important updates from The Michael J. Fox Foundation regarding events, …

… to determine if the mutant SGK1 protects neuronal cells from cell death caused by the mutant LRRK2. These results … Understanding how mutant SGK1 protects people with LRRK2 from getting PD by determining if this mutation causes the …

… be test for their ability to rescue dopaminergic neurons from rotenone- (oxidative) and alpha-synuclein-mediated … levels of wild-type, but not mutant, DJ-1 protect neurons from oxidative stress and other PD related insults. DJ-1 …