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Novel Nicotinic Receptor Agonist for Treating Levodopa-induced Dyskinesia
… therapeutic benefit as a treatment of levodopa-induced dyskinesias. This proposal is intended to extend and …
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Managing Levodopa-induced Dyskinesias by Targeting Dopamine D1 Receptor Signaling
… to replenish dopamine can cause motor side effects called dyskinesias. Laboratory studies suggest these dyskinesias …
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The Role of Subclinical Rejection in Graft-mediated Dyskinesias
… the replacement cells developed debilitating 'off-medicine' dyskinesias. Dyskinesias are unwanted, excessive, …
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D3 Receptor Selective Drugs for Parkinson's Dyskinesia
… strategy to prevent or delay the onset of levodopa-induced dyskinesia in early-onset Parkinson's patients is to treat … symptoms of both Parkinson's disease and levodopa-induced dyskinesia. Our project investigates the possible use of D3 …
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Glycosylated Opioid Peptides For the Treatment of Levodopa-Induced Dyskinesias
… develop disabling side effects known as levodopa-induced dyskinesia which causes disruptive involuntary movements of … Parkinson's disease with the aim of stopping troublesome dyskinesias. Anticipated Outcomes: We will produce …
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Validation of Dyskinesia Rating Scales
… Objective/Rationale: Dyskinesias, or involuntary jerking movements, are …