-
Targeting Serotonin Transporters for the Treatment of Levodopa-induced Dyskinesia Supplement
… Serotonin Transporters for the Treatment of L-DOPA-induced Dyskinesia Promising Outcomes of Original Grant: Initial … transporter (SERT) for the treatment of levodopa-induced dyskinesia (LID) revealed, as hypothesized, that blocking …
-
Effects of KCNQ (Kv7) Channel Openers in Levodopa-induced Dyskinesias
… of Kv7 channels and the pathophysiology of levodopa-induced dyskinesias, openers of these channels may provide novel …
-
Optimization of Dopamine D4 Antagonists for the Treatment of Levodopa-induced Dyskinesia
… Study Rationale: Levodopa-induced dyskinesia is a major dose-limiting effect associated with … preventing the development or reversing levodopa-induced dyskinesia in PD. To this end, the objective of this project …
-
Simvastatin for the Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
… Objective/Rationale: Levodopa-induced dyskinesias are caused by an increased response of dopamine …
-
Flibanserin in Levodopa-induced Dyskinesia: MPTP-lesioned Pre-clinical Model
… or writhing-like twisting and turning movements called dyskinesias which appear after years of levodopa treatment …
-
Role of 5-alpha Reductase 1 in the Therapy of Neurodegeneration and Levodopa-induced Dyskinesias
… occur in Parkinson's disease and reduce the severity of dyskinesias. Dyskinesias are one of the major complications …