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Preventing Misfolded Alpha-synuclein Accumulation
… in PD. Next Steps for Development: Positive findings from this study would support development of novel …
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Targeting RER1 in Models of Parkinson's Disease
… on Diagnosis/Treatment of Parkinson's Disease: The findings from these studies should lead to a better understanding of …
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Network Models of Neurodegeneration (NetMON)
… of neurodegenerative diseases that will influence decisions from treatment to care. Next Steps for Development: Clinical …
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Studying GBA Pseudogene as a Controller of GBA and Alpha-synuclein
… Design: We will generate stem cells and then nerve cells from cells donated by people with Parkinson’s disease with …
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Generation of Transgenic Mice with Selective and Progressive Loss of Nigrostriatal Dopaminergic Neurons
… as proposed, but did not show significant differences from previously generated alpha-synuclein transgenic mice. …
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Targeting LRRK2 for Parkinson's Disease
… disease are not clearly established, information gained from rare genetic mutations has provided insights into basic …