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Development of a Radioligand for Imaging of Alpha-synuclein with Positron Emission Tomography
… capability to bind to alpha-synuclein in human brain tissue from people with Parkinson´s disease. Impact on …
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External Validation of Proteos Alpha-synuclein Pre-formed Fibrils
… studies could examine whether preformed fibrils generated from alpha-synuclein could provide the ideal fibril species …
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Promoting Mitochondrial Transport in Dopaminergic Neurons
… starting point for developing therapies that prevent cells from degenerating by increasing their ability to ship …
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Rab Detection Initiative and LRRK2 Detection Initiative Supplemental Support RDI, and LCC exosome replication
… This grant builds upon the research from a prior grant: Rab Detection Initiative Study …
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Peripheral Inflammatory Cytokine Profiling in Parkinson's Disease
… We will measure inflammation in blood samples obtained from an international consortium managed by The Michael J. …
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Validation of USP30 as a Therapeutic Target for Parkinson's Disease Modification
… models of Parkinson's disease. If positive data comes from theses studies, Mission may consider progression toward …