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Sex-Related Longitudinal Change of Motor, Non-Motor, and Biological Features in Early Parkinson's Disease
January 21, 2022
… non-motor burden of disease, with possible contributions from suboptimal dopaminergic therapeutic response in men. …
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Evaluation of Gene Products that Counteract the Action of LRRK2
… enzyme, called a phosphatase, to remove phosphate groups from Rab proteins, reversing the activity of LRRK2. Study …
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Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation
June 16, 2021
… the LRRK2 phosphosite S935. Candidate phosphatases selected from the primary screen were tested in mammalian cells, …
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Establishing the Therapeutic Potential of Engineered Neural Circuits in a Preclinical Model of Parkinson’s Disease
… studies are important for advancing our engineered circuits from the bench to the bedside. The data we gather will be …
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PPMI: The Study that Could Change Everything (Webinar)
December 29, 2021
… and what scientists know about the brain. In this audio from our Third Thursdays Webinar, expert panelists discuss …
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Examining Fatty Acid Imbalances in Parkinson’s Disease
… to re-establish fatty acid balance in neurons derived from people with PD and other preclinical PD models and …