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Optimization of Optical Coherence Tomography as a Biomarker for Parkinson's Disease
… neural part of the eye, the retina in patients suffering from Parkinson Disease and in healthy, age matched subjects. … Patients diagnosed with Parkinson Disease and not suffering from eye disease will be examined and the back of their eye …
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Evaluation of the Neuroprotectivity Ability of Zymes' Water-soluble CoQ10 (WS-CoQ10) in Pre-clinical Models of PD; Preclinical Validation and Dose Optimization for Clinical Study
… consisting of CoQ10 and vitamin E (WS-CoQ10), licensed from the National Research Council Canada. This formulation … in the management of neurodegeneration: lessons from the application of water-soluble Coenzyme Q10 …
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Novel alpha-Synuclein Isomers as Immunogens for Immunotherapy of Parkinson Diseases
… with native alpha-synuclein as a control immunogen. Results from the first assay showed that all three isomers displayed … models in each group but the variability did not result from the measurement itself because every measurement was …
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Neuroimaging Markers Predict Cognitive Decline in PD
… for cognitive impairments and dementia in PD. Results from this study will have an immediate impact on clinical … Patterns of amyloid deposition distinguish non-demented PD from normal aging. Presented at the Human Amyloid Imaging …
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Specificity & Sensitivity of Transcranial Ultrasound as Biomarker in Parkinson's Disease
… marker may help to distinguish patients with idiopathic PD from patients with atypical Parkinsonian syndromes. However, … solely through application of TCS whether a person suffers from PD or not. In the second study, patients with clinical …
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Development of the Alpha-Synuclein Stabilizer NPT200-11 for the Treatment of Parkinson’s Disease
… whether or not this compound, that prevents alpha-synuclein from taking on toxic conformations in vitro , also prevents … explanation for how clearing misfolded alpha-synuclein from cell membranes may result in improved neuronal …