… such as the striatum. Oxytocin may reverse levodopa-induced dyskinesias by reducing the activity of a subset of neurons …

… with serious motor complications called levodopa-induced dyskinesia (LID). Once established, LID is very hard to … 50 PD patients without LID. The severity of disease and dyskinesia will be scored using the Unified Parkinson’s …

… models have an altered onset of levodopa induced dyskinesia, a major side effect that occurs after chronic … been linked to the development of levodopa induced dyskinesia are changed.  We will also investigate whether a …

… eventually result in the development of levodopa-induced dyskinesia in most Parkinson’s disease (PD) patients. But … acetylation, moderates the severity of levodopa-induced dyskinesia in PD patients without altering parkinsonian …

… Objective/Rationale:              Dyskinesia (involuntary fractured, jerky movements) is a … movement) can decrease the expression of levodopa-induced dyskinesia in pre-clinical models. This study will …

… Objective/Rationale:              Levodopa-induced dyskinesias are abnormal involuntary movements that may …