… Study Rationale: Chronic sleep disruption is among the most frequently reported and … features of Parkinson’s disease (PD). This loss of sleep quality is driven by dysregulation of the … a protein called CK1, plays a key role in regulating sleep and has been extensively characterized using …

…                During the rapid eye movement (REM) phase of sleep, when we dream, our voluntary muscles are paralyzed so that we would not act out our dreams. In REM sleep behavior disorder (RBD), patients lose this ability. … to be involved in Parkinson’s disease (PD) and REM sleep Behavior disorder (RBD), we expended the panel of …

… Objective/Rationale: Sleep related problems are a major cause of impairment in … Recent studies indicate a high incidence of a disabling sleep disorder – sleep disordered breathing (SDB; known also as obstructive …

… down the path to diagnosis: acting out his dreams, or REM sleep behavior disorder (RBD). This sleep condition is a lesser-known symptom of Parkinson's … and diagnosis by years or even decades. What Is REM Sleep Behavior Disorder? In REM sleep behavior disorder, a …

… Fatigue and trouble sleeping can come from Parkinson's, its symptoms or the … them. There are many approaches to managing fatigue and sleep changes, and researchers are working toward better … they feel exhausted but they don't necessarily feel like sleeping. They're tired physically and sometimes mentally, …

… act out their dreams. They may punch, kick or yell while asleep. This condition is called REM sleep behavior disorder or RBD. Sleep problems, including RBD, are common with Parkinson's. …