The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2007Ethics of Sham Surgery Controls to Test Novel Parkinson's Disease Interventions
Objective/Rationale:
When experimental treatments involve neurosurgery, researchers often use a placebo condition called sham surgery, which involves an invasive procedure (e.g., partial thickness... -
Rapid Response Innovation Awards, 2007Re-distribution of Brain Gangliosides for Treatment of Parkinson's Disease
Project Description:
A pre-clinical model of Parkinson's disease can be generated by injecting MPTP, a toxin that results in specific damage to the same part of the brain that is damaged in Parkinson's...
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Rapid Response Innovation Awards, 2007Nanoparticle Gene Therapy for Parkinson's Disease
In this research project we will determine the feasibility of condensing plasmid DNA into nanoparticles and using these nanoparticles to deliver their payload into cells of the central nervous system...
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Rapid Response Innovation Awards, 2007A Novel Strategy for the Selection and Transplantation of Dopamine-Specified Human Embryonic Stem Cells
In Parkinson’s disease (PD), neurodegeneration is largely confined to one discrete group of nerve cells that produce the chemical dopamine (DA). Since the death of most DA neurons almost always...
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Community Fast Track, 2007Neoangiogenesis and Blood-Brain Barrier in L-DOPA-Induced Dyskinesia
Levodopa is still the most effective treatment for Parkinson's disease, but has a great potential to induce abnormal involuntary movements (dyskinesia).
Working on a pre-clinical model of PD, we have...
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Rapid Response Innovation Awards, 2007Aberrant Striatal Morphology: Impact on Therapeutic Efficacy in PD
While recent clinical trials of neural grafting for Parkinson’s disease (PD) are disappointing, rationale for "replacing" brain cells lost to disease remains strong. Many issues thought to underlie...
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Our funding programs support basic, translational and clinical research from academia and industry.