The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Biosample Use Program, 2021Evaluating Neurotoxic Metabolites as Biomarkers of Parkinson’s Progression
Study Rationale:
Individuals with Parkinson’s disease (PD) show elevated markers of inflammation in their brains, cerebrospinal fluid and blood. We think that inflammation drives the worsening of... -
PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2021Characterization of PET Tracers for Alpha-synuclein and 4R Tau
Study Rationale:
Parkinson’s disease (PD) is a brain disease characterized by slow movement, rest tremor and stiffness. In most cases the underlying cause is an aggregation of a protein called alpha... -
Target Advancement Program, 2021Pathogenic Mechanisms for Auxilin-mediated Parkinson's Disease
Study Rationale:
Parkinson’s disease (PD) is a prevalent neurodegenerative movement disorder. Several genetic mutations that cause PD have been identified in patients. One such mutation targets... -
Therapeutic Pipeline Program, 2021Proof of Concept and Translational Validation of USP30 to Offset Dysfunction in the PRKN Pathway
Study Rationale:
USP30 is an enzyme which acts in the opposite way to Parkin (PRKN), a gene linked to young-onset Parkinson’s disease (PD). Mutations in the PRKN gene impact mitochondria (the cell’s... -
Research Grant, 2021Bipolar Disorder and Parkinson’s Disease
Study Rationale:
Mood disorders are common in people with Parkinson’s disease (PD) and, in many cases, precede motor symptoms and diagnosis by years. The relationship between bipolar disorder and PD... -
Therapeutic Pipeline Program, 2021Using Virtual Reality to Understand and Treat Freezing of Gait
Study Rationale:
Freezing of gait, an episodic inability to initiate movement, is a leading reason for loss of independence in Parkinson’s disease (PD). Despite its prevalence, we lack an effective...
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Our funding programs support basic, translational and clinical research from academia and industry.