The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies, 2022Development of Immune-based Biomarkers for Parkinson’s Disease
Study Rationale: Preclinical and human studies have demonstrated the potential of using granulocyte-macrophage colony-stimulating factor (GM-CSF) for the treatment of Parkinson’s disease (PD). GM-CSF...
-
Fall 2021 RFP: Outcome Measures, 2021Development and Validation of a Sensitive Method for Measuring PINK
Study Rationale: Mutations in PINK1 are linked to familial Parkinson’s disease (PD), but their role in sporadic forms of the disorder are not clear. The PINK1 protein works with PRKN to dispose of...
-
Research Grant, 2021Exploring the Protective Effect of Modulating Brain Cells’ Electrical Activity in Parkinson’s Disease
Study Rationale: The symptoms of Parkinson’s disease (PD) arise when more than 70% of the dopamine-producing neurons in the brain region regulating movement are lost. This disruption increases the...
-
Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Studying How Defects in Autophagy Contribute to the Aggregation of Alpha-synuclein in Neurons with LRRK2 Mutations
Study Rationale: Mutations in the LRRK2 gene are the most frequent cause of inherited forms of Parkinson’s disease (PD). We have found that these mutations disrupt autophagy—a process that cells...
-
Fall 2021 RFP: Outcome Measures, 2021Characterization of Sterols in CSF and Plasma as a Possible Biomarker for Parkinson’s Disease
Study Rationale: Sterols, including cholesterol, are very abundant in the brain, where they form important components of cell membranes and act as signaling molecules within and between cells...
-
Fall 2021 RFP: Expanding Biological Understanding of PD, 2021Using Human iPSC to Explore the Role of the STING Pathway in Parkinson's Disease
Study Rationale: Inflammation is recognized as a factor in the progression of Parkinson’s disease (PD). The PD-associated genes PINK1 and Parkin are involved in eliminating damaged cell components...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.