The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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ASAP CRN Competitive Renewal Opportunity, 2024Studying the Cortical Pathophysiology of Parkinsonism
Study Rationale: Activity changes in nerve cells in the brain’s cerebral cortex are central to Parkinson’s disease (PD). However, which specific cell types are affected, and how and when their...
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ASAP CRN Competitive Renewal Opportunity, 2024Understanding and Manipulating Cellular and Circuit-level Vulnerability to Neurodegeneration in Parkinson’s Disease
Study Rationale: Many people with Parkinson’s disease (PD) develop untreatable cognitive symptoms due to changes in the brain’s cerebral cortex. These symptoms, which include problems with attention...
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Research Grant, 2024(SUPPLEMENT) Disparities in Neurocognitive Impairment among Hispanics/Latinos in the US with Parkinson’s Disease: The Role of Cardiovascular Risk
Study Rationale: In the United States, Latinos with Parkinson’s disease (PD) are more likely to have problems with memory, planning and other thinking skills than people with PD of other ethnic/racial...
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Accelerating Biological Understanding and Therapeutic Translation for PD-Biology, 2024Using A Screening Platform Based on Induced-pluripotent Stem Cells to Study Parkinson’s Disease
Study Rationale: This project represents a supplement to our MJFF project, “Shedding Light on the Dark Genome in Parkinson’s Disease (PD).” For the initial project, we developed a suite of...
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Measuring Alpha-Synuclein in Extracellular Vesicles, 2024Development of an Alpha-synuclein Blood Biomarker for Clinical Use
Study Rationale: In Parkinson’s disease (PD), alpha-synuclein forms abnormal clumps in nerve cells, causing their death. By the time people develop PD, these alpha-synuclein aggregates have spread...
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2021 RFA: PIPETTE 4R Tau and Alpha-Synuclein PET Tracer Development, 2024SUPPLEMENT: Rescreening of the MJFF Compound Library to Identify Molecules that Can be Used to Monitor Alpha-synuclein
Study Rationale: Alpha-synuclein is a key protein involved in the pathology of Parkinson’s disease (PD). We recently confirmed that two compounds developed under the MJFF Alpha-synuclein Imaging...
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Our funding programs support basic, translational and clinical research from academia and industry.