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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Improved Neuromodulation Approaches, 2014
    Chronic Directional Deep Brain Stimulation in Parkinson’s Disease

    Study Rationale:       
    The side effects of deep brain stimulation (DBS) in Parkinson’s disease are related to overstimulation of the brain target structure and neighboring regions. This clinical study...

  • Research Grant, 2014
    Phase IIb Study of Intranasal Glutathione in Parkinson's Disease

    Study Rationale:
    The loss of glutathione in the brain of individuals with PD occurs years before the onset of motor symptoms. Glutathione has been proposed as neuroprotective therapy in PD for decades...

  • Research Grant, 2014
    Role of Striatal Cholinergic Interneurons in Parkinson’s Disease Dyskinesia

    Study Rationale:                   
    In pre-clinical models, we identified an important role of cholinergic interneurons — which release the neurotransmitter acetylcholine — from part of the brain...

  • Research Grant, 2014
    Gene Expression Changes in Striatal Cholinergic Interneurons Associated with Levodopa-induced Dyskinesia

    Study Rationale:                   
    In pre-clinical models, we identified an important role of cholinergic interneurons — which release the neurotransmitter acetylcholine — from part of the brain...

  • Research Grant, 2014
    Development of an MgluR4 PET Radioligand

    Study Rationale:                   
    mGluR4 is a glutamate receptor that is believed to be a potential therapeutic target for Parkinson’s disease (PD). Developing an imaging tracer may allow researchers...

  • Rapid Response Innovation Awards, 2014
    Improving Gait in Parkinson’s Disease Patients by Non-invasive Electrical Stimulation of the Cerebellum

    Study Rationale:
    People with Parkinson’s disease (PD) can experience difficulties walking (e.g., freezing), which can lead to falls and negatively impact quality of life. These symptoms are difficult...

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