The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2017Radioactive Molecules for Detection of Alpha-synuclein and Amyloid-beta in the Brain
Study Rationale:
We will develop radioactive alpha-synuclein and beta-amyloid tracers -- molecules that allow researchers and clinicians to detect these two proteins in the brain using imaging... -
Access to Data & Biospecimens, 2017Klotho and Parkinson’s disease
Study Rationale:
Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...
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LRRK2 Biology Consortium, 2017The Role of Variations in the LRRK2 Gene in Parkinson's Disease
Study Rationale:
Genes can influence one's chance of developing Parkinson's disease (PD), but it's not entirely clear how. In this study, we will use cells from people with Parkinson's to test how the... -
Access to Data and Biospecimens, 2017LRRK2 in predicting Parkinson disease risk and progression in LRRK2 mutation carriers
Study Rationale:
The G2019S mutation in the LRRK2 gene is responsible for thousands Parkinson disease (PD) cases. But, not all of the mutation carriers will develop PD. Currently, clinicians...
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Research Grant, 2016Investigation of the Role of PINK1-dependent Phosphorylation of Rab GTPases in Parkinson’s Disease
Study Rationale:
Mutations in the PINK1 gene lead to Parkinson’s disease. PINK1 belongs to a special class of enzymes known as protein kinases. We recently found that PINK1 targets a family of enzymes... -
Priority Target Award, 2016Advancing PINK1 Knockout Models of Parkinson’s
Study Rationale:
Loss-of-function mutations in PINK1 are causally linked to early-onset Parkinson’s disease (PD). MJFF funded the generation and initial characterization of PINK1 knockout (KO) models...
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Our funding programs support basic, translational and clinical research from academia and industry.