The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2018Charting a Path to Success for Clinical Trials in Patients with Inherited, GBA-linked Parkinson's Disease: PPMI Supplement
Promising Outcomes of Original Grant:
The original study is ongoing.Objectives for Supplemental Investigation:
We aim to determine whether fatty molecules called sphingolipids can serve as biomarkers --... -
Rapid Response Innovation Awards, 2014Optogenetics-based, Photo-switchable Model of Parkinson’s Disease for Drug Screening
Objective/Rationale:
Neurodegeneration has proven notoriously difficult to study. The main barrier to progress has been the challenging, heterogeneous nature of brain tissue. Optogenetics is a... -
Community Fast Track, 2003Regulation of Dopaminergic Pathways by Eph Family Receptors
Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...
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Postural Instability and Gait Disturbances, 2009Determining the Neural Correlates of Freezing of Gait in Parkinson's Disease Using Functional Magnetic Resonance Imaging
Objective/Rationale:
Freezing of Gait (FOG) in Parkinson’s disease occurs when a person’s feet become suddenly ‘frozen’ while walking or turning. FOG is a leading cause of falls, and responds poorly to... -
Research Grant, 2024Validation of Functional Staging of Parkinson’s Disease Using the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
Study Rationale: Researchers recently proposed defining Parkinson’s disease (PD) based on a test for abnormal alpha-synuclein in spinal fluid and adopting a staging system based on measures (or scales...
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Biomarkers Across Neurodegenerative Diseases, 2014Cortical and Functional Distinctions in Alzheimer’s and Parkinson’s Diseases
Study Rationale:
Alzheimer’s disease (AD) and Parkinson’s disease (PD) are clinically distinct disorders, but their pathologies overlap considerably. Understanding how these overlaps relate to the two...
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Our funding programs support basic, translational and clinical research from academia and industry.