The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Access to Data & Biospecimens, 2017Klotho and Parkinson’s disease
Study Rationale:
Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...
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Community Fast Track, 2004The role of nociceptin/orphanin FQ in regulation of motor behavior and induction of parkinsonism
Nociceptin/orphanin FQ (N/OFQ) is an opioid-like neuropeptide discovered in the mid 90's, which activates a G-protein coupled receptor, the NOP receptor. N/OFQ and its receptor are diffusely expressed...
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LRRK2 Cohort Consortium Resource Request, 2013Alpha-synuclein and Other Biomarkers in Biological Samples of LRRK2 Parkinson’s Disease
Objective/Rationale:
Cerebrospinal fluid (CSF) biomarkers of Alzheimer’s pathology have been investigated in Parkinson’s disease (PD), and abnormal CSF protein levels (tau and phosphorylated tau, beta... -
Research Grant, 2013Longitudinal Characterization of G2019S Models: Physiological and Behavioral Analyses of Dopamine and Glutamate Systems
Objective/Rationale:
It is likely in disease states that brain cells suffer long periods of dysfunction before they die. By studying the early effects of Parkinson’s disease (PD) gene mutations upon... -
Research Grant, 2024Validation of Functional Staging of Parkinson’s Disease Using the Critical Path for Parkinson’s (CPP) Integrated Parkinson’s Database
Study Rationale: Researchers recently proposed defining Parkinson’s disease (PD) based on a test for abnormal alpha-synuclein in spinal fluid and adopting a staging system based on measures (or scales...
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Postural Instability and Gait Disturbances, 2009The Role of White Matter Pathology in the Development of the Postural Instability and Gait Disturbance (PIGD) Type of Parkinson's Disease (PD)-1
Objective/Rationale:
It is not clear why a subset of patients with Parkinson's disease develop postural instability and gait disturbances (PIGD), while others do not. White matter (WM) changes that...
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Our funding programs support basic, translational and clinical research from academia and industry.