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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Computational Science, 2017
    Analyzing Data from the Parkinson’s Progression Markers Initiative to Identify Subtypes of Parkinson’s Disease

    Study Rationale:
    Parkinson's disease (PD) presents and progresses variably, so no two people with Parkinson's have the same disease. The diversity of PD clinical manifestations makes the disease more...

  • Access to Data & Biospecimens, 2017
    Klotho and Parkinson’s disease

    Study Rationale:                   

    Genetic studies have identified a powerful “aging suppressor gene”, Klotho, that may play a role in delaying age-related declines in cellular and tissue functioning...

  • Biomarker Development, 2015
    Biomarker and DNA Samples Collection Add-on Study to the Phase III Trial of Isradipine

    Study Rationale:
    Isradipine, an FDA-approved agent for treatment of high blood pressure, was shown to be have neuroprotective benefit in models of Parkinson’s disease (PD).  A recently completed Phase...

  • Therapeutic Pipeline Program, 2015
    Inhibitors of Alpha-synuclein Oligomers for the Treatment of Parkinson’s Disease

    Study Rationale:
    The alpha-synuclein protein forms oligomers (protein clumps) that cause toxicity in the brains of individuals with Parkinson’s disease (PD). We have developed methods that can measure...

  • Access to Data and Biospecimens, 2014
    Analysis of Circulating Brain-Enriched microRNA as Biomarkers for Parkinson’s Disease

    Study Rationale:                   
    Early detection of neurodegenerative diseases can lead to more effective therapeutic intervention. DiamiR proposes a diagnostic approach based on analysis of...

  • Research Grant, 2013
    Virtual Research Visits

    Objective/Rationale:             
    The Michael J. Fox Foundation’s Fox Trial Finder is designed to facilitate and increase the participation of individuals with Parkinson’s disease in clinical trials...

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Our funding programs support basic, translational and clinical research from academia and industry.

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