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Funded Studies

Austen James Milnerwood, PhD

Assistant Professor in Neurology and Translational Neuroscience at University of British Columbia

Location: Vancouver BC Canada

Austen James Milnerwood, PhD, is an assistant professor in neurology in the Centre for Applied Neurogenetics at the University of British Columbia. He has >14 years of experience investigating neuronal transmission and cellular models of learning and memory in the healthy and diseased brain. Dr. Milnerwood’s PhD focused on developmental synaptic plasticity and the temporal evolution of neurophysiological disturbances in Huntington’s disease and his ongoing investigations have lead to successful therapeutic intervention against early pathophysiological processes. His current program of research centers on investigations of basic synaptic connectivity and genetic models of neurodegeneration, including fronto-temporal lobar dementia and Parkinson’s disease. Dr. Milnerwood’s team has a large research effort dedicated to LRRK2 neurophysiology, and the effects of Parkinson’s disease-related LRRK2 mutations. He has received fellowships from The Michael Smith Foundation for Health Research, The Canadian Institutes for Health Research, The Bluma Tischler Foundation, The Huntington’s Disease Society of America, The Huntington Society of Canada and much of his research is grant funded by The Canadian Institutes for Health Research and The Michael J Fox Foundation.

Associated Grants

  • Alpha-synuclein Toxicity in LRRK2 Knock-in Models and Rescue by LRRK2 Silencing


  • Alpha-synuclein Toxicity in LRRK2 Pre-clinical Models and Rescue by LRRK2 Silencing


  • Role of LRRK2 in Dopamine Modulation of Striatal Glutamate Transmission


  • Longitudinal Characterization of G2019S Models: Physiological and Behavioral Analyses of Dopamine and Glutamate Systems


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