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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • GBA Biology and Therapies, 2019
    Resolving the Pathophysiology of Parkinson's Disease with GBA Mutations

    Study Rationale:
    Mutations in the GBA gene are the greatest genetic risk factor for developing Parkinson’s disease (PD). We will systematically examine pathophysiological pathways in PD patients with...

  • Research Grant, 2013
    Virtual Research Visits

    Objective/Rationale:             
    The Michael J. Fox Foundation’s Fox Trial Finder is designed to facilitate and increase the participation of individuals with Parkinson’s disease in clinical trials...

  • Access to Data and Biospecimens, 2014
    Analysis of Circulating Brain-Enriched microRNA as Biomarkers for Parkinson’s Disease

    Study Rationale:                   
    Early detection of neurodegenerative diseases can lead to more effective therapeutic intervention. DiamiR proposes a diagnostic approach based on analysis of...

  • Neuronal Synuclein Disease Endotypes 2024, 2025
    Testing Biofluid Samples from the Arizona Study of Aging and Neurodegenerative Disorders for Alpha-synuclein and Biomarkers of Alzheimer’s Disease

    Study Rationale: The Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) has amassed a comprehensive collection of samples and longitudinal clinicopathological data. In this project, we...

  • Fast Track, 2002
    Comparitive gene expression analysis of the brain in Parkinson's Disease and in familial encephalopathy with neuroserpin inclusion bodies (FENIB): implications for pathogenesis

    Parkinson's disease (PD) is a common neurological disorder that affects the control of movement and frequently cognition. Examination of postmortem brain tissue from subjects with Parkinson's disease...

  • Research Grant, 2016
    GBA Meta-analysis Initiative: Charting a Path to Success for Clinical Trials in Patients with GBA-PD

    Promising Outcomes of Original Grant:
    We ascertained the associations between GBA mutations and cognitive and motor outcomes in seven large cohorts representing 2,304 patients with PD (including 221...

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