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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • LEAPS, 2003
    High Resolution Whole Genome Study to Determine Genetic Loci of Parkinson's Disease

    The Cox team will leverage Perlegen's high-density array technology and the Mayo Clinic's extensive patient database, clinical expertise and DNA bank to create a genetic map of causes and risk factors...

  • Community Fast Track, 2003
    Regulation of Dopaminergic Pathways by Eph Family Receptors

    Replacing dopaminergic neurons is an attractive alternative in the treatment of Parkinson's disease (PD). However, a successful treatment relies not only on the introduction of new neurons, but also...

  • Community Fast Track, 2002
    Proactive action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a pre-clinical model model of Parkinson's disease

    Recently, in mouse studies the peroxisome proliferator-activated receptor-g (PPARg) agonist pioglitazone was shown to be effective in blocking the substantia nigra (SN) cell loss induced by MPTP in a...

  • Biomarkers, 2002
    Peripheral Benzodiazepine Receptor: An In Vivo Biomarker of Parkinson's Disease

    The goal of the proposed studies is to validate an early marker of Parkinson's disease (PD) that may be able to identify disease onset prior to clinical manifestation. It is now recognized that in PD...

  • Biomarkers, 2002
    Simple Blood Tests for Parkinson's Disease Derived from Genome-wide Expression Changes

    The diagnosis of Parkinson's disease relies on expert opinion. Autopsy studies, however, have demonstrated that even experienced neurologists misdiagnose Parkinson's disease in about a quarter out of...

  • Biomarkers, 2002
    State & Trait Markers for Parkinson's Disease in CSF, Plasma, & Urine from Datatop

    Although the clinical features of Parkinson's disease (PD) and its changes in the brain are unmistakable, it lacks identified biochemical clues that could enhance early diagnosis of this disorder. We...

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