The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2025SUPPLEMENT: Cytokine Production by Adaptive Immune Cells from Patients with Parkinson’s Disease: Response to Diverse Biological Stimuli
Study Rationale: Studies demonstrate a role for the adaptive immune system (T-cells and B-cells) in PD. The rationale for this study is that by using enriched T-cells and B-cells and exposing the...
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Research Grant, 2025First-in-human Evaluation of [11C]UCB-1A as Imaging Marker for Vesicle Glycoprotein 2C (SV2C): a PET Study in Healthy Volunteers and in Subjects with Parkinson’s Disease
Study Rationale: Parkinson’s disease (PD) damages brain connections early on, linked to accumulation of a protein called alpha-synuclein. We aim to track this accumulation using a new brain imaging...
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T2T Validation - NOD2, 2025Assessing the Role Played by NOD2 in Murine Models of PD
Study Rationale: Brain inflammation has been associated with the development of Parkinson’s disease (PD). In search for factors that may influence inflammation that triggers PD, several groups have...
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Parkinson’s Disease Therapeutics Pipeline Program, 2025SUPPLEMENT: A Novel Immunotherapy for the Treatment of Parkinson’s Disease
Study Rationale: There is currently no treatment that slows or stops the progression of Parkinson’s disease (PD). We are developing a novel therapeutic approach that targets neuroinflammation and...
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Research Grant, 2024SUPPLEMENT: Development of a Protein Biomarker Panel to Measure Parkinson’s Disease Activity and Progression
Study Rationale: Managing and treating Parkinson’s is extremely challenging without the right tools and insights. According to the Michael J. Fox Foundation, “the need for objective Parkinson’s...
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De-risking Therapeutic Development for NOD2
Summary of Target and Rationale for Funding: NOD2 is a signaling protein that plays a central role in regulating immune and inflammatory pathways. Preliminary genetic data suggest a potential link...
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Our funding programs support basic, translational and clinical research from academia and industry.