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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • Ask the MD: What Is Lewy Body Dementia?

    Do Different Genders Experience Different Types of Parkinson’s?

    A paper exploring differences in Parkinson’s symptoms and progression between men and women was published in the journal Movement Disorders.

  • Two researchers in lab looking at samples

    PPMI Dispatch: Closer to Predicting Disease Progression and Symptoms

    Findings from our Parkinson’s Progression Markers Initiative study point to potential ways to measure progression and predict disease.

  • Research Testing

    PPMI Dispatch: Identifying Differences in Disease Profiles and Impact on Quality of Life

    Findings from the Parkinson’s Progression Markers Initiative show differences in symptoms among participants with genetic mutations and compare automatic functions over time with quality of life.

  • Scientist in Lab

    PPMI Dispatch: Streamlined Data, Genetic Indicators and Cognitive Decline Predictors

    Data from the Parkinson’s Progression Markers Initiative has been downloaded more than 5 million times. View recent findings and updates from the study.

  • Theresa Lin, Sarah Simon, Katherine Leaver, Sonya Elango, Susan Bressman, Deborah Raymond, Rachel Saunders-Pullman

    Research Community Thanks Parkinson’s Study Participants

    Research volunteers advance understanding and treatment of Parkinson’s disease. Foundation staff and partners recently thanked local participants.

  • Samples in the lab.

    PPMI Dispatch: Early Signs of Disease and Striking Some Potential Markers

    Findings from the Parkinson’s Progression Markers Initiative show subtle symptoms in mutation carriers and that motor subtypes change with time and therapy.

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