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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • PPMI Data Shows Brain Changes Linked to Parkinson's Progression

    Data from Landmark MJFF Study Shows Impact of Promising Parkinson’s Therapy

    PPMI data on expected disease progression in Parkinson’s contrasts slower change in treatment group. Learn more.
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  • PPMI AIM Conference 2024

    The Study that Keeps Changing Everything: Dispatch from the PPMI Annual Meeting

    The Parkinson’s Progression Markers Initiative (PPMI) acknowledged a year of significant milestones in Parkinson’s disease (PD) research at its annual meeting in early May.
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  • Bill Bucklew smiling

    An Open Letter from Someone With Smell Loss

    MJFF Patient Council member shares his experience with smell loss, which can be an early signal of Parkinson’s disease.
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  • Marcy Schaeffer

    My Research Journey: Doing my Small Part to Support People with Parkinson’s

    Marcy Schaeffer, 68, is a volunteer in the Foundation’s landmark Parkinson’s Progression Markers Initiative (PPMI). She lives with smell loss, which can be an important signal of risk for Parkinson’s…
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  • people sitting classroom style

    PPMI Dispatch: Study Leaders Meet to Chart the Future of Parkinson’s Research

    More than 300 study leaders gathered in New York City for the annual PPMI meeting. They discussed scientific findings from study data and next steps for future research, with a focus on the…
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  • Allen in Venice

    My Research Journey: How an RBD Diagnosis, Not Parkinson’s, Led to Joining a Landmark Study

    Allen Dance shares his experience with REM sleep behavior disorder and how it led him to the Parkinson’s Progression Markers Initiative.
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