Resources
To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Rab 8 pT72 Phosphospecific Antibody (Non-Selective)
Rabbit monoclonal phosphospecific antibody directed against Threonine72 of the human Rab 8 protein. Suitable for immunoblot and immunoprecipitation experiments. Note: Cross reacts with threonine-phosphorylated Rabs 3, 10, 35, and 43.
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LRRK2 G2019S Mouse
Transgenic mice overexpressing a mutant form (G2019S) of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene. RRID:IMSR_JAX:018785
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LRRK2 Antibody (8G10)
Mouse monoclonal antibody directed against wild-type LRRK2 using a fragment of LRRK2 (AA 100-500)
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Rat Alpha-Synuclein Monomer Protein for Making Pre-Formed Fibrils
Full-length rat alpha-synuclein monomeric protein specially formulated to generate pre-formed fibrils.
Please note: Validation of the rat alpha-synuclein monomers for making pre-formed fibrils identified a lack of pathology in vitro in mouse primary hippocampal neurons and in vivo in rat. Email tools@michaeljfox.org with questions or for more information.
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LRRK2 A2016T Mouse
Mice expressing the A2016T mutant (kinase inhibitor resistant) form of LRRK2. RRID:IMSR_JAX:021828
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LRRK2 Antibody (UDD3)
Rabbit monoclonal antibody directed against the N-terminus (LRRK2(100-500)) of wild-type LRRK2. This antibody has been found to be superior in immunoprecipitation of LRRK2 from a variety of cell lysates and tissues.
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Mouse Alpha-Synuclein Monomer Protein for Making Pre-Formed Fibrils
Full-length mouse alpha-synuclein monomeric protein specially formulated to generate pre-formed fibrils. Please note, we recommend this protein for in vitro studies but not for in vivo experiments (the protein as validated for pS129 alpha-synuclein pathology in vitro but in vivo validation failed as robust pS129 alpha-synuclein pathology was not observed).
Note: A protocol for generating pre-formed fibrils from this monomeric protein will be included with each order.
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Total Rab 8 Antibody
Mouse monoclonal antibody directed against the human total Rab 8 protein. Suitable for immunoblot and immunostaining experiments. Epitope was mapped to amino acids 101-108.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic