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Funded Studies

Birgitt Schüle, MD, Dr. med.

Associate Professor at Stanford University School of Medicine

Location: Stanford, CA United States

Birgitt Schüle, MD, is an associate professor in the Department of Pathology at Stanford University School of Medicine. Her research focuses on medical genetics and stem cell modeling to unlock disease mechanisms and pathways leading to neurodegeneration in Parkinson’s disease and related disorders for the development new therapeutic strategies.

Dr. Schüle received her medical degree from the Georg‐August University Göttingen and Medical University Lübeck, Germany (1993 ‐ 2001) and completed her doctoral degree in medicine (Dr. med.) in neurophysiology at University of Göttingen (2001). During her neurology internship from 2001 to 2002 at Medical University of Lübeck with Prof. Christine Klein, Dr. Schüle studied inherited forms of Parkinson’s disease and dystonia. Between 2003 and 2005, she was a postdoctoral fellow in the Department of Genetics at Stanford University School of Medicine with Prof. Uta Francke. From 2005‐2019, Dr. Schüle led three clinical research programs at the Parkinson’s Institute: neurogenetics, translational stem cell modeling and brain donation program.

Associated Grants

  • Assessment of LRRK2 Activity and Neurodegeneration Markers in Postmortem Brain Samples of Idiopathic and LRRK2-associated Parkinson’s Disease


  • Functional Evaluation of Alpha-synuclein Dosage Effects in CRISPR‐edited SNCA Model


  • CRISPRi/dCas9 Downregulation of Alpha-synuclein as a Novel Gene Therapy


  • Stem Cells with Different Amounts of Alpha-synuclein as a Drug Discovery Tool


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