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Funded Studies

Chadwick Wilson Christine, MD

Professor of Neurology at University of California San Francisco

Location: San Francisco, CA United States

Dr. Christine completed his medical degree with honors in research at Cornell in 1991. He completed his neurology residency at UCSF in 1995 and then conducted his research fellowship in synaptic plasticity.

Since 1999, he has developed far-ranging interests in Parkinson’s disease. His research interests include: 1) discovery of the risk factors for Parkinson’s, 2) identification of factors that affect Parkinson’s progression, and 3) improvement of Parkinson’s treatments.

Dr. Christine’s research has included participation in both medical and surgical treatment studies, and he has recently been involved in a study of novel biomarkers for Parkinson’s. He was an investigator in several Phase 1 studies and now Phase 2 of a gene therapy study for advanced Parkinson’s disease, which utilizes the gene for amino acid decarboxylase, the enzyme that converts levodopa into dopamine. His most recent work explores the relationship between low vitamin B12 status and the development of gait impairment in Parkinson’s.

Associated Grants

  • Relationship of Plasma Vitamin B12 and Homocysteine Levels with Outcomes in SURE-PD and STEADY-PD Trials


  • Relationship of Vitamin B12 Status and Parkinson's Disease


  • Phase I Study of AAV2-hAADC Administered by MRI-guided Real-time Convective Infusion


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